Für mich kämen nur GenCoin Projekte in Frage

Amos, Sonntag, 20.03.2016, 23:27 (vor 3596 Tagen) @ Onkel S.5595 Views
bearbeitet von Amos, Sonntag, 20.03.2016, 23:38

Hallo Onkel S.

ich würde mich aus ethischen Gründen nur an GenCoin Projekten beteiligen.
Die ganze Rechenkraft die die Miner aufwenden, müsste sinnvoll umgeleitet werden.
Ein neuer GenCoin entsteht nur dann, wenn ein neues SNP Mapping zu einer Krankheit gefunden wurde.
Gibt es eventuell so ein Projekt bereits? Dann würde ich dort gerne mitmachen. Der persönliche Gencode könnte zugleich mittels 2 Faktor Authentifizierung als "Private Key" dienen, damit ich in jedem Fall immer an meine Coins ran komme.

Hier nur mal ein Beispiel zu Multible Sklerose, der Header der "Raw-Daten" stammt in diesem Fall von der Firma 23andMe:

# This data file generated by 23andMe at: Sat Mar 11 05:21 2016
# This file contains raw genotype data, including data that is not used in 23andMe reports.
# This data has undergone a general quality review however only a subset of markers have been
# individually validated for accuracy. As such, this data is suitable only for research,
# educational, and informational use and not for medical or other use.
# Below is a text version of your data. Fields are TAB-separated
# Each line corresponds to a single SNP. For each SNP, we provide its identifier
# (an rsid or an internal id), its location on the reference human genome, and the
# genotype call oriented with respect to the plus strand on the human reference sequence.
# We are using reference human assembly build 37 (also known as Annotation Release 104).
# Note that it is possible that data downloaded at different times may be different due to ongoing
# improvements in our ability to call genotypes. More information about these changes can be found at:
# https://www.23andme.com/you/download/revisions/
# More information on reference human assembly build 37 (aka Annotation Release 104):
# http://www.ncbi.nlm.nih.gov/mapview/map_search.cgi?taxid=9606
#
# rsid chromosome position genotype
rs4477212 1 82154 AA
rs6897932, located in the alternatively spliced exon 6 of IL7RA gene and encoding the amino acid threonine rather than isoleucine at amino acid position 244, is associated with a slight increase (18%) in risk of developing multiple sclerosis. [PMID 17660817; Nature Genetics 39, 1083 - 1091 (2007) SG Gregory et al.]
Note that the (C) allele is the most common at this position in all known populations and influences the ratios of the alternative isoforms (membrane bound and soluble) of the gene.
[PMID 17660817] a significant risk factor for multiple sclerosis in four independent (overall P = 2.9 x 10(-7)) influences the amount of soluble and membrane-bound isoforms of the protein by putatively disrupting an exonic splicing silencer.
[PMID 18721276] A replication case-control study involving 599 patients with multiple sclerosis yielded a per allele odds ratio of 1.32 per rs6897932(C), (CI: 1.1-1.6, p = 0.0031), and odds per (C;C) genotype vs (T;T) and (C;T) genotypes of 1.5 (CI: 1.18-1.87, p = 0.0007).


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